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Amyloid- aggregation is accompanied by ROS formation, including peroxyl radicals, responsible for the lipid peroxidation process and the formation of 4-hydroxynonenal (HNE)

Vitamin C acts as a glutathione recycler, regenerating the reduced (active) form from the oxidized form

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Abstract Schizophrenia (SZ) is a biochemically complex disorder characterized by widespread defects in multiple metabolic pathways whose dynamic interactions, until recently, have been difficult to examine

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As expected, ABT had no effect on TCDD-induced CYP1A1 expression (Fig 5D), in agreement with the fact that TCDD is poorly metabolized and has a half-life of ~5 years in adults [31]