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Coenzyme Q10, oxidative stress markers, and sperm DNA damage in men with idiopathic oligoasthenoteratospermia

Together, these biomarkers not only offer mechanistic insight into diabetes-induced male infertility, but also provide promising avenues for early detection, disease monitoring, and therapeutic response evaluation

The phase 2 trial has demonstrated the favorable safety profile of the drug 23 , whereas one phase 3 trial (NCT04587908, jRCT2041200055) is currently ongoing

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However, our data showed that Gln deprivation did not induce apoptotic cell death within a short period of time, such as 24 h