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Blinding was not used because the primary readouts in this study were based on objective measurements, including sequencing-based datasets, GPCR activity assays, metabolite quantification and flow cytometry, for which investigator awareness of group assignment was unlikely to influence data collection or analysis

10.1038/nn.4476 38 FuscoW.BriccaL.KaitsasF.TartagliaM

Devos D, Moreau C, Devedjian JC, Kluza J, Petrault M, Laloux C, et al

Gupta S, Aziz N, Sekhon L, Agarwal R, Mansour G, Li J, Agarwal A

Of the patients with depression, 28 had moderate depression and 43 had severe depression at the time of the study