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Concurrently, GSH reduces Fe 3 + to Fe 2 + , which activates S 2 O 8 2 to generate highly toxic sulfate (SO 4 ) and hydroxyl radicals, inducing coordinated ferroptosis and pyroptosis in lung cancer cells 219

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(32) followed 14 patients with PD-associated mild cognitive impairment during an 8-week KD and found an improvement in lexical access and memory, and a nonsignificant trend toward reduced memory interference (32)

clinical presentation of high-risk (massive) poisoning Patients develop mitochondrial dysfunction very early (usually within 30 grams) may present with mental status alteration and lactic acidosis within 12 hours of ingestion