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1969 Nov 6;37(4):5936

170 Similarly, in lipopolysaccharide (LPS)-induced acute liver injury, IL-22 activates ATF4, which promotes ATG7 expression and LC3-II conversion, reducing inflammation through autophagy

The resulting casein-derived phosphoproteins (Boggs et al., 2015) and -casein fragment -CN 128 (Silanikove et al., 2000) inhibit K-secretion by closing K-channels and disrupting the tight junctions between milk-secreting cells to induce dry-out (Nguyen & Neville, 1998)