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Certain tumor cells during breast cancer chemotherapy show upregulation of SASP genes, followed by an augmented expression of PD-L1 and CD80, immunosuppressive molecules, within cancer cells

Injection Site Irritation : Local mild irritation at the injection site is the consistently reported physical reaction across preclinical toxicity studies

Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, et al

Clearance takes longer in elderly patients, those with liver impairment, and CYP2C19 poor metabolizers

Anti-Inflammatory Effects Chronic inflammation is often the root of fatigue, pain, and disease

And one of the polysaccharides, glycomannan, is linked to fibroblast stimulation + collagen synthesis