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[58] Medical uses [edit] Treatment of deficiency [edit] Severe vitamin B 12 deficiency is initially corrected with daily intramuscular injections of 1000 g of the vitamin, followed by maintenance via monthly injections of the same amount or daily oral dosing of 1000 g

(i) the multigenerational exposure to a Novosphingobium diet being necessary to induce TEI of the predatory mouth form, (ii) the capability of vitamin B12 supplementation to induce TEI of this phenotype, and most importantly (iii) the concentration-dependent effect of vitamin B12 supplementation

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CNS Drug Rev 11:353368

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