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Here, similarly, we also showed that the three-weeks deep-frying oil treatment increased the number of steatosis, induced oxidative stress marked by the depletion of endogenous antioxidant expression, and causing oxidative damage as shown by the elevation of liver function marker (AST and ALT) as well as lipid peroxidation marker (hepatic and systemic MDA)

2011 Apr;43(2):80-6

PMID: 37024456 Cell Death Dis Irisin protects against vascular calcification by activating autophagy and inhibiting NLRP3-mediated vascular smooth muscle cell pyroptosis in chronic kidney disease