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A critical review on the interactions of microplastics with heavy metals: Mechanism and their combined effect on organisms and humans

Mevalonate pathway alterations and targeting in MM Statins are well-known inhibitors of HMGCR as well as of the mevalonate pathway rate-limiting enzymes, which are crucial for cell growth and survival

Journal of the American College of Nutrition, 20 (6), 591598

It results in emergence of pathogenic peptides, which cause CD and allergy in genetically predisposed people

AIF plays a dual role in regulating cell survival and apoptosis: its translocation to the nucleus causes caspase-independent apoptosis in response to death stimuli, while in the mitochondria, AIF maintains OXPHOS function via posttranscriptional regulation of respiratory chain complexes through its NADH oxidoreductase activity [31, 32]

Ischemia-reperfusion injury (IRI) IRI followed by reperfusion can induce massive cell death and inflammatory response in affected organs, resulting in severe diseases including IRI-induced heart disease, kidney diseases, lung diseases and liver diseases [242]