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2 Biosynthesis of melanin and its regulation 2.1 Melanin synthesis pathway The specific process of melanin synthesis begins with the conversion of tyrosine into L-Dopa catalysed by tyrosinase, the central glycoprotease in the melanosome region and the only rate-limiting enzyme in this process (Kim et al., 2023)

Despite preliminary evidence pointing towards their significance (Dayon et al., 2017), other elements of the OCM pathway, namely those of the methionine cycle, have traditionally received relatively limited academic attention

Conversely, wheat husk has frequently been incinerated or utilized as livestock feed and fertilizer

We are also grateful to the personnel of the Rodent House animal facility (IGBMC) for their assistance with animal handling and care