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Oxidative stress can also aggravate intestinal flora disorders in the body

Then, tissues were digested in a solution composed of collagenase I (450 U/ml, C0130), collagenase XI (125 U/ml, C7657), DNase I (60 U/ml, D5319-500UG), and hyaluronidase (60 U/ml, H3506, all Sigma Aldrich) in PBS for 1 h under agitation at 37C

MetaboAnalyst 5.0: Narrowing the gap between raw spectra and functional insights

doi: 10.1046/j.1468-2982.2002.00412.x 84

Second, during energy metabolism, mitochondria produce ROS and other free radicals that can accumulate excessively and damage cell membranes, proteins, and DNA, thereby accelerating neuronal degeneration (Swerdlow, 2018)

However, L-carnitine treatment corrected such inflammatory responses