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Data analysis The Comprehensive Meta-analysis software was utilized to process the data extracted from the included studies

Therefore, in the present study, universal distribution, toxicity of HMs and their emergence in the food chain, uptake and transport, detoxification mechanisms in plants, and ways of crop improvement under HM stress conditions have been explored

X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production

In mice, a GCLC deficiency leads to embryonic death (Maher 2006)

Abstract Ferroptosis is a type of regulated cell death characterized by iron accumulation and uncontrolled lipid peroxidation, leading to plasma membrane rupture and intracellular content release

Disturbances in redox homeostasis within the cardiovascular system directly promote oxidative stress ( Copper may exacerbate oxidative stress by stimulating ROS production and participating in the Fenton reaction