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This breakdown is typically associated with the disintegration of collagen fibers, frequently resulting from either tissue damage or the natural degradation process

Immunofluorescence results showed a significant increase in FOXO4 and p53bp1 foci within the nucleus of senescent cells compared to those in dividing cells (Figure

doi: 10.1021/acs.jmedchem.5b00992

For persistent or severe symptoms Any side effect that worsens over time, spreads beyond the application area, or is accompanied by systemic symptoms like fever, malaise, or swollen lymph nodes requires professional evaluation

9:e101186

Therefore, NPs are specially designed to facilitate their transport across the BBB and provide therapeutic effects against certain neurological diseases like AD, PD, stroke, and brain tumors [241]