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Limited clinical trial data to justify its use in COVID-19 Most of the clinical studies where NAC has been used (either alone or in combination with another drug) tend to focus on its use as a mucolytic in two population subgroups: paediatric populations at lower doses where its antioxidant effects are less evident (6) with studies dating mainly from the 1970s and 1980s of low quality evidence

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In line with this, by using whole-exome sequencing on diffuse large B-cell lymphoma patients, a loss of the chromosomic region including CT2 gene in half of the patients has been shown

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These typically resolve within a few days