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Introduction The global water cycle faces unprecedented anthropogenic stress, with aquatic ecosystems increasingly serving as the ultimate sinks for a vast array of contaminants originating from the technosphere.14 The relentless expansion of industrialisation and intensive agriculture discharges a complex mixture of chemical stressorsranging from heavy metal cations (e.g., Cd2+, Hg2+, Pb2+) to bioactive micropollutantsposing a profound threat to ecological stability.57 Legacy water treatment infrastructures are fundamentally ill-equipped to eliminate these recalcitrant contaminants, which often persist at trace concentrations (ng L1 to g L1) yet exert potent biological effects

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Because glutathione is used up as it does its job, levels are sustained over time rather than fixed in a single visit

PLoS ONE 4 , e6313 (2009)

Fucoxanthin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE and Nrf2-autophagy pathways

385 Mito-TEMPO (MT), another mitochondrial superoxide scavenger, also prevents muscle atrophy via alleviating mitochondrial dysfunction, oxidative stress and inflammatory