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Other secondary criteria of efficacy assessing the benefit on LDRC included change in MDS-UPDRS 24 fluctuations with dyskinesia and dystonia part IV (the highest being the worst)

The cells were collected in the medium with 10 M Y-27632 (Fujifilm Wako Pure Chemical Corporation) and centrifuged

5.2.1 AMPK activation and improvement of metabolic homeostasis: metformin Metformin primarily exerts its pharmacological effects by activating AMPK and suppressing hepatic gluconeogenesis, thereby restoring glucose metabolic homeostasis

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Qualifications: - Medical degree (MD or DO) from an accredited institution

doi: 10.1016/j.ijbiomac.2019.09.185 148 ZhuangCWangYZhangYXuN