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The hydrogen peroxide produced by this reaction is then decomposed into harmless water and oxygen by CAT and GPx ( The second line of defence comes from non-enzymatic antioxidant components such as glutathione (GSH), metal binding proteins (MBPs) and uric acid (UA) which rapidly inactivate reactive species and thereby prevent the propagation of chain reactions ( To summarise, the human body has to maintain a delicate balance of forming enough reactive species to perform useful physiological roles, whilst breaking down the excess to prevent unnecessary cellular damage

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Nutrient acquisition by pathogenic fungi: nutrient availability, pathway regulation, and differences in substrate utilization

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Cell 19 , 829840 (2005)