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After the regression of the second wave, the fear of a possible third wave is high

The occurrence of bone erosion during the progression of RA is closely related to the ROS-induced upregulation of nuclear factor of activated T cells 1 (NFATc1), a regulator of osteoclast activity and bone resorption in rats, which promotes RANKL-induced osteoclastogenesis and the differentiation of mouse bone marrow macrophages (BMMs) into osteoclasts

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We also thank the Boston Childrens Hospital Hematology/Oncology and Harvard Stem Cell Institute Flow Cytometry Research Laboratory for their services, as well as the Genomic Perturbation Platform at the Broad Institute

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