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National Research Council (2000)

PMID: 11101503)

The absence of evidence in this case is not an accident

Bortezomib in cancer therapy: mechanisms, side effects, and future proteasome inhibitors

(1997).Increased nuclear ploidy, not cell proliferation, is sustained in the peroxisome proliferator-treated rat liver

Real-world example: This distinction explains why someone who skipped a glass of water at dinner probably isnt experiencing a meaningfully different BAC than if theyd had that glass but someone who spent three hours in the sun at a summer festival without drinking any water, then started drinking alcohol, is in a genuinely different physiological state