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10.1136/ard.2006.054593 Summary Keywords glutathione peroxidase-3, activity, inflammation, antineutrophil cytoplasmic antibody, vasculitis Citation Chung J, Ha JW, Park Y-B and Lee S-W (2025) Serum glutathione peroxidase-3 concentration at diagnosis as a biomarker for assessing disease activity and damage of antineutrophil cytoplasmic antibody-associated vasculitis at diagnosis

Schimmer AD, Thomas MP, Hurren R, Gronda M, Pellecchia M, Pond GR, Konopleva M, Gurfinkel D, Mawji IA, Brown E, Reed JC

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This epigenetic silencing can lock T cells into an exhausted state and impair memory T cell differentiation, weakening long-term immunity ( 3.2.1Succinate Accumulation and HIF-1 Stabilization Damage to the ETC, particularly at Complex II (succinate dehydrogenase), can lead to the accumulation of succinate