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For example, Paclitaxel (Shen et al., 2008), Doxorubicin (Nagy et al., 1998), and Camptothecin (Sun et al., 2008) were conjugated to octreotide analogs and provided impressive toxicities and selectivity for SSTR2 and SSTR5 expressing cells in vivo

A number of factors contribute to the development of PD, including, environmental changes, aging, chronic diseases, and social disadvantage (Schrag et al., 2015)