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To investigate mechanisms underlying FTLD-GRN, single-cell transcriptomics in the thalamus and frontal cortex of Grn / mice and FTLD-GRN patients identified a conserved astrocytic pathology marked by upregulation of GJA1, AQP4 , and Apoe , and downregulation of the glutamate transporter SLC1A2

Circadian regulation of physiological processes: reciprocal signaling between the clock and other regulatory networks In addition to their primary role as generator of circadian rhythm, the biological clock serves a key role in controlling physiological functions of almost all tissues and organs in two major ways

doi: 10.1152/physrev.00044.2005 5 Bernal-CondeL

Gyermek, L., Soyka, L

3-Nitrophenyl hydrazine based quantification of kynurenine and tryptophan The sample preparation 3-Nitrophenyl hydrazine (NPH) derivatization method was carried out as described in [56, 57]

Yoshitake, T., et al