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Kaestner S, Sewell G

Involvement of disulfide bond formation in the activation of heparanase

In human colorectal adenocarcinoma cells, aspartame was shown to increase epithelial barrier permeability and induce ROS production, effects that were attenuated by knockdown of the T1R3 receptor

L.RuprechtM.SchleiffE.et al (2016)

Studies have also shown that PI3K/Akt1/mTOR signal pathway is involved in regulating the proliferation of pulmonary artery smooth muscle cells (PASMCs) in PH (51)

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