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Macrophage polarization, metabolic reprogramming, and inflammatory effects in ischemic heart disease

Grison, A

M9a + sh EPAS1 cells upregulate HIF-1-BNIP3/NIX-mediated mitophagy and suppress mtDNA-mediated inflammation under hypoxia condition Hypoxia-induced mitophagy is typically mediated by BNIP3/NIX and regulated by HIF-1 [28], so we first excluded the involvement of PINK1/PARKIN-mediated mitophagy in Tibetan hypoxia adaptation (Supplementary Fig

Ginger (Zingiber officinale) phytochemicals-gingerenone-a and shogaol inhibit SaHPPK: molecular docking, molecular dynamics simulations and in vitro approaches

Exposure to Light Ultraviolet (UV) radiation can induce oxidation and structural changes in amino acid chains

19,23,24 The absence of clearly defined diagnostic criteria for PGA has complicated efforts to comprehend its biological mechanisms and create specific therapeutic approaches for this subtype