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Some assays developed and utilized to this endpoint are cell cycle, mitochondrial membrane potential, thiol status, lysosomal integrity Cytometry Use of flow cytometry/sorting, scanning laser cytometry, confocal laser cytometry, image analysis and multispectral imaging to assay various cell lines and tissues utilizing fluorescent and colormetric dyes/markers to elucidate toxicological endpoints that relate to environmental health factors and exposures in human health