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224 The decrease in GSH and GPX4 leads to increased tissue damage in animal models of ferroptosis and diabetes

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This is also one of the main mechanisms for the non-regenerative anemia in chronic kidney disease

Lewis K, Lutgendorff F, Phan V, Sderholm JD, Sherman PM, McKay DM (2010) Enhanced translocation of bacteria across metabolically stressed epithelia is reduced by butyrate

2-Deoxyglucose (2-DG) is a glucose analog that is transported to cells and metabolized by hexokinase (HK) to form 2-DG-P

Generally, most dietary polyphenols undergo hydrolysis by colonic bacteria and are then methylated and conjugated into glucuronide and sulfate metabolites by the hepatic and other tissues (106)