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10.3390/nu10060762 25 CroughsM.Van GompelA.RameckersS.Van den EndeJ

introduced a thioketal bond to connect camptothecin [60](CPT) with the photosensitizer 2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide a (HPPH), forming a ROS-responsive prodrug (CPT-TK-HPPH)