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Additionally, selenium may act as an immunostimulant, activating immune cells and counteracting immune checkpoint-mediated immunosuppression within the tumor microenvironment ( Figure 2 )

Body Composition Assessment Body mass index (BMI) is the assessment tool used worldwide to estimate the degree of overweight or obesity [37]

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doi: 10.3389/fcell.2016.00016 Received 29 November 2015 Accepted 22 February 2016 Published 23 March 2016 Volume 4 - 2016 Edited by Gaetano Santulli, Columbia University in the City of New York, USA Reviewed by Yves Combarnous, Centre National de la Recherche Scientifique, France

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