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Research has shown that EGFR is highly expressed in various tumor cells, particularly in TNBC, where its overexpression is closely associated with aggressive features such as high invasiveness, increased risk of distant metastasis, and poor prognosis (Yin et al., 2020)

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Synthesized in the liver, fibrinogen plays a host of roles in human physiology, including blood clot formation, fibrinolysis, inflammation, wound healing, cellular and matrix interactions, and neoplasia