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In enterocytes, hypoxia-inducible transcription factor (HIF-2), a mediator of cellular adaptation to hypoxia, has been shown to regulate iron absorption after changes in systemic iron levels via direct transcriptional activation of DMT1, DCYTB, and FPN (Shah et al., 2009[381]

10.1016/j.biopha.2023.115669 Summary Keywords autophagy, melatonin, mitochondrial dynamics, mitochondria-related diseases, oxidative phosphorylation Citation Lei X, Xu Z, Huang L, Huang Y, Tu S, Xu L and Liu D (2024) The potential influence of melatonin on mitochondrial quality control: a review

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Peppermint essential oil (food-grade) 1-2 drops in water

7 Discussion Among these compounds, EDV and saikosaponins exhibit the most robust multi-target mechanisms and have demonstrated direct efficacy in depression models

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