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Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have ever had an allergic reaction to similar medicines in the past, or suffer from bone loss (osteoporosis)

The injection must be given by a healthcare professional

Standalone cobalamin supplements carry the highest doses, often 500 to 1,000 mcg per tablet, while B-complex and multivitamin products contain considerably less

Elderly patients should be reassured that most side effects are minor and that the benefits of correcting B12 deficiencypreventing irreversible neurological damage and anaemiafar outweigh these temporary inconveniences

Finally, one very recent study in the USA has demonstrated that in some individuals with neurological symptoms, the presence in the blood of antibodies against this receptor may interfere with the proper uptake of B12 into the brain

BMC Medical Research Methodology 2005;5:13