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John Costello, M.D.: If you catch it at an early phase, if you stop the patient smoking, if you take the patient away from the polluted environment that may be contributing to it, and you treat it actively, another form of treatment that I haven't mentioned, but in terms of prognosis becomes important is rehabilitation

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287 It was shown whether MG-63 cells were treated with berberine and cisplatin alone or combination, the MAPK signaling was inhibited manifested by the downregulation of expression of p-p38, p-JNK, and p-ERK