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Description

5.2 Biomarker enrichment membranes and biosensor integration The same nanotopography-enabled enrichment principles that improve CTC recovery can be repurposed as upstream concentration modules for a broader range of low-abundance biomarkers, enabling integrated sensing workflows for longitudinal gastric cancer monitoring ( Beyond CTC enumeration, gastric cancer surveillance increasingly relies on longitudinal tracking of multiple low-abundance signals, including circulating proteins, nucleic acids, extracellular vesicles, and inflammatory mediators