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(4) The peptide was suggested to significantly lower ROS levels, unlike higher concentrations that did not demonstrate similar protective actions

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Germande O, Ducret T, Quignard JF, Deweirdt J, Freund-Michel V, Errera MH, Cardouat G, Vacher P, Muller B, Berger P, Guibert C, Baudrimont M, Baudrimont I (2022) NiONP-induced oxidative stress and mitochondrial impairment in an in vitro pulmonary vascular cell model mimicking endothelial dysfunction

On the other hand, using metyrapone, a CORT synthesis inhibitor, reduced blood corticosterone levels in Lurcher mice, but did not affect their behavioral disinhibition [205]

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