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The FDA is publishing this data to improve transparency and provide additional information to regulated industry and the public The US Food and Drug Administration (FDA) introduced an important data update to approved drug products with therapeutic equivalence evaluations known as the Orange Book. Search results and drug listings will show patent submission dates where available

[1] Berberine is a bioactive alkaloid compound extracted from several plants, including Berberis species (barberry), goldenseal, and Chinese goldthread

Preclinical studies have shown restoration of memory function and enhanced synaptic connectivity in Alzheimer models

Rev Neurol (Paris) 157:679681 Angelet P, Compte MT, Cid JL, Soriano T, Vilaseca J, Bartolom J (2000) Episodios recurrentes de acidosis con encefalopata en un paciente en programa de hemodilisis con sndrome del intestino corto

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