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Several of these, including proteoglycan core proteins, sialo-glycoproteins, surface glycoproteins, and glycosaminoglycans (GAGs), constitute endothelial glycocalyx and are essential for tissue integrity (34)

Use of rat models to predict sex differences in human responses to xenobiotics is not reliable, since inter-individual variations among humans outweigh any sex-dependent responses

These lipid species are actively secreted (via exosomes or free diffusion) or passively released through necrosis, creating a lipid-rich TME that directly modulates immune cell fate and function

Furthermore, ALC acts as a potent antioxidant, helping to safeguard brain cells from oxidative deteriorationmaking it highly beneficial for targeted memory support and other age-related cognitive applications