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*Correspondence: Qian Yu, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

doi: 10.1016/j.trecan.2021.02.004 Summary Keywords metabolic reprogramming, phosphoglycerate dehydrogenase (PHGDH), serine metabolism, serine synthesis pathway (SSP), targeted therapy, tumor immune microenvironment Citation Su P, Yang Y and Zheng H (2026) The serine code of metabolic reprogramming: multidimensional roles of the serine synthesis pathway in tumors and novel breakthroughs for targeted therapy

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