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Dose escalation follows a gradual titration schedule to minimize gastrointestinal adverse effects, the most common being nausea, vomiting, and diarrhea

LL-37 is generated from a much larger precursor protein known as hCAP-18 (human cationic antimicrobial protein, 18 kilodaltons)

The multiplicity of cells and mediators thought to be involved in the pathogenesis of COPD is presented schematically in Figure 4-2

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The in-vivo data are overwhelmingly rodent

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