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Since 1978, Immunocal has been awarded 92 patents, and its foundational science has been validated in peer-reviewed medical journals and clinical trials worldwide

: Alterations of mononuclear inflammatory cells, CD4/CD8+ T cells, interleukin 1beta, and tumour necrosis factor alpha in the bronchoalveolar lavage fluid, peripheral blood, and skin of patients with systemic sclerosis

Reiss AL, Faruque F, Naidu S, Abrams M, Beaty T, Bryan RN, et al

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Based on the nucleotide sequences of the target genes, development of primer sets were designed and used to amplify gene fragments by PCR (Additional file 1: Tables S1S6)