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This work was supported by grants from Margareta af Ugglas foundation (M.R.), the Swedish Research Council (M.R., N.M., A.K

Accordingly, this system could be developed for various clinical applications, including the treatment of familial short stature, cancer cachexia, eating disorders, and sarcopenia (Kojima and Kangawa, 2005)

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No additional indications have been approved beyond HIV-associated lipodystrophy, though ongoing research continues into NAFLD, cognitive function, and other metabolic applications

Coronary and arterial plaque (atherosclerosis) develops gradually as cholesterol particles such as LDL in the blood are "lipid oxidized" and damage the blood vessels' lining, forming a plaque