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doi: 10.1158/2326-6066.Cir-17-0375

Similarly, anti-inflammatory glucocorticoid dexamethasone was loaded into a mixture of poly(1,4-phenyleneacetonedimethylene thioketal) and polythioketal urethane to form nano-scaled particles, and the polymers' abundant thioketal bonds broke down when activated by ROS in LPS-impaired lungs after i.v

This critical and unique property allows the RDLA to be absorbed in the gastrointestinal tract and distributed through the bloodstream (which is mostly water) to all cells of the body where it can diffuse through the cell membrane, which is made of fat molecules

Tammadon MR, Nobahar M, Hydarinia-Naieni Z, Ebrahimian A, Ghorbani R, Vafaei AA (2021) The effects of valerian on sleep quality, depression, and state anxiety in hemodialysis patients: a randomized, double-blind, crossover clinical trial