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Additionally, mitochondrial dysfunction contributes to osteoporosis by increasing ROS levels which disrupt the balance between bone formation and resorption [60,61,66,67]

Its rich composition of growth factors, cytokines, and nutrients supports tissue regeneration, reduces inflammation, and enhances healing processes

Thereafter, 5 l FITC-conjugated Annexin-V and propidium iodide (PI) were added to the cells, vortexed, and incubated at 25C in the dark for 10 min

The brain, deprived of the depressant it has adapted to, becomes overexcited

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However, clinical subscores assessing components of neuropathy, such as distal muscle weakness alone, or a combination of weakness, reflexes and sensory changes in the arms and legs or legs alone, showed some marginal improvement from baseline in the intervention group