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However, the molecular mechanisms underlying this phenomenon remain largely unclear

[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Gao XM, et al

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Together, these findings support a model in which GSTs exert bidirectional control over pyroptosis with GSTM1 and GSTP1 dampening inflammasome execution, whereas GSTO1 derepresses inflammasome assembly