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Moreover, the hypoxia factor HIF-1 induces upregulation of mitochondrial Lon and promotes IL-6 secretion through indirect effects on STAT3 72

Mechansim of gamma-hydroxybutyic acid production during the early postmortem period

10.1089/08977150360547080 104 HardyJ.SelkoeD

Experimental response: Application of the chemical directly to the target cells should produce the same response observed when the chemical is naturally released from neurons

Environ Health 17:23

Targeting this transcription factor has been shown to have therapeutic advantages in a mouse model of influenza strain H5N1 leading to a drastic reduction in NF- regulated cytokines (89)