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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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This supports previous studies demonstrating metformin-mediated radiosensitisation of HCT116 colon cancer cells ( The precise mechanisms underpinning the observed radiosensitising effects of metformin treatment in cancer are poorly understood

Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors

We performed a detailed analysis of RRM2 expression based on TNM stages and pathological types using the TCGA data, When cases were grouped by pathological subtype, RRM2 expression was higher in classic and tall-cell variants of papillary thyroid carcinoma compared with the follicular variant

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