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To view a copy of this licence, visit About this article Cite this article Gu, S., Wang, H., Liu, H

In parallel, causal in vivo studies targeting key structural regulators of these contact sites, such as MFN2 and other tethering proteins, will be particularly informative for determining whether disruption of organelle interaction hubs directly contributes to mitochondrial dysfunction, metabolic imbalance, and functional ovarian decline

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Reduced apoptosis is often associated with the development of cancer, and finding agents that can restore programmed cell death in cancer cells is considered a potential therapy for cancer