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P = 0.63 respectively)

A growing body of evidence reveals pervasive iron homeostasis disruption and elevated lipid peroxidation in the cartilage, subchondral bone, and synovial tissue of OA patients, correlating positively with disease severity and cartilage damage

[DOI] [PubMed] [Google Scholar] Leo MA, Kim CI, Lowe N, Lieber CS

Additionally, miR-9 contributes to AD pathogenesis by inducing ferroptosis through targeted inhibition of SLC7A11, thereby blocking GSH synthesis, and additionally participates in regulating NFTs formation (220)

APD-elevated glucagon may therefore drive the hyperglycemic states that these drugs produce since glucagon receptor KO mice are protected against APD-induced hyperglycemia independently of changes in insulin levels 21

A review on the roles and molecular mechanisms of MAFG-AS1 in oncogenesis