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Acknowledgments Thanks to the editors and reviewers for their hard work and important comments

Chronically activated microglia in ALS gradually lose their immune functions and develop unconventional proteome

In addition, COX-2 is the main trigger of oxidative and inflammatory responses that are often detected in photoaging and other stress/inflammatory disorders (138)

Glycopolypeptide coordinated nanovaccine: fabrication, characterization, and antitumor immune response

Research shows its chemical stability gives consistent results across different time points

Dysregulation of this axis leads to a self-perpetuating cycle of inflammation, oxidative stress, and tissue damage