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Codoer et al., 2018

Lower CK19 expression was detected in cirrhotic vs early-stage (IF 0-2) PP regions (164.2 vs 305.1, p =0.044)

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In the HD model, although propionic acid treatment could temporarily inhibit cortical inflammatory factors (such as TNF- and iNOS), it could not prevent the progression of neuronal death or mitochondrial dysfunction, 314 suggesting the dose-dependent toxicity of SCFAs

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Early AD is characterized by A plaques, tau hyperphosphorylation, and glial cell activation, leading to neuroinflammation and cognitive decline (23)