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Unlike normal cells, cancer cells proliferate rapidly and are unable to respond to cell death signals that initiate apoptosis

Peripheral inflammatory signals can access the central nervous system through humoral, neural, and cellular pathways, including cytokine transport across the bloodbrain barrier and vagal nerve signaling, thereby initiating or amplifying central immune activation (31)

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Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study

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Kamei R, Okabe S